Nirmatrelvir with ritonavir (Paxlovid®) for patients with COVID-19

Nirmatrelvir with ritonavir (Paxlovid®) is now available for patients with COVID-19 who are at high risk of severe disease. This bulletin discusses drug interactions that can occur with ritonavir, some of which may be potentially life-threatening.

Further information on use of Paxlovid® can be found at:

Health professionals are welcome to contact our service for more specific advice on individual patients.