Bulletins - COVID-19
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Drug Interactions with nirmatrelvir-ritonavir (Paxlovid®) - April 4, 2022
Nirmatrelvir-ritonavir is a combination medicine used to treat COVID-19 infections. Ritonavir increases (boosts) the concentration of nirmatrelvir by inhibiting its clearance by CYP3A enzymes. This also increases the concentration of other drugs metabolised by CYP3A. This is why drug interactio...