Christchurch Medicines Information Service

Treatment of pain in pregnant and breastfeeding women should follow the same principles as for all adults, using the analgesic ladder: Step 1: Paracetamol and/ or NSAID, e.g. ibuprofen or diclofenac Step 2: Add a weak opioid for mild to moderate pain, e.g. codeine, tramadol Step 3: Chang...

Background Pfizer state in their prescribing information that both nirmatrelvir and ritonavir tablets should be swallowed whole and not chewed, broken, or crushed. [1] This is due to a lack of pharmacokinetic data to support administration in this manner. However, a Phase 1 study with a nirmatre...

Probenecid was introduced in the 1950’s to reduce the renal elimination and extend the plasma half-life of penicillins. This effect is exploited therapeutically in the treatment of cellulitis and other infections. It is also used for gout prophylaxis, in light of its uricosuric effects. Prob...

Note this bulletin is older than 5 years old and the content may no longer be accurate

Note this bulletin is older than 5 years old and the content may no longer be accurate

Note this bulletin is older than 5 years old and the content may no longer be accurate

Note this bulletin is older than 5 years old and the content may no longer be accurate

Note this bulletin is older than 5 years old and the content may no longer be accurate

Note this bulletin is older than 5 years old and the content may no longer be accurate

Note this bulletin is older than 5 years old and the content may no longer be accurate