Handling of Hazardous Medicines by Healthcare Workers

October 2025

This bulletin classifies the hazardous medicines available in Aotearoa, and provides information on safety measures to protect healthcare workers by minimising occupational exposure.

Drug-Induced QTc Interval Prolongation

September 2025

This bulletin helps to assess the risk of drug-induced QTc interval prolongation and includes links to useful resources.

Dabigatran Etexilate in Compliance Aids

March 2025

Did you know two studies have recently been published (including one from Aotearoa!) exploring the stability of dabigatran etexilate in compliance aids? This bulletin is an update of our 2018 version, and summarises the key findings from these new studies.

Cannabis-Based Products

February 2025

Confused about cannabis? Consolidate your knowledge with our new bulletin on Cannabis-Based Products

Absorption of medicines following bariatric surgery

November 2024

Bariatric surgery has become increasingly common and has the potential to affect the absorption of medicines. This bulletin explains the types of procedures usually undertaken in Aotearoa and the effects these may have on physiological and pharmacokinetic changes.

Analgesia during pregnancy or while breastfeeding

November 2024

This bulletin discusses treatment options for acute pain in people who are planning pregnancy, pregnant, or breastfeeding. While most guidance has not changed, we now suggest to consider avoiding non-steroidal anti-inflammatories (NSAIDs) around the time of conception. It also discusses the controversy with codeine use while breastfeeding.

Assessing medicines when stored outside manufacturer recommendations

August 2024

This bulletin provides a framework for considering whether medicines stored for short periods outside manufacturers specifications remain suitable for use.

Medicines and Meals – Food for Thought?

June 2024

The timing of medicine administration in relation to food is not important for most medicines, and patients should generally be advised to take their medicines consistently at the same time with respect to meals. This bulletin explores some of the myths around food and medicines, and highlights examples where an interaction with food may be clinically significant.

SGLT2 Inhibitors and GLP-1 Receptor Agonists

January 2024

SGLT2 inhibitors and GLP1 receptor agonists are being used increasingly in NZ for type 2 diabetes and other conditions such as heart failure and obesity. This bulletin gives an overview of these two classes of medicines.

Can transdermal patches be halved?

May 2023

Sometimes it is necessary to give a lower patch dose than is available. This bulletin discusses preferred methods for halving patch doses, and the risks and benefits of this practice.

Antidepressant Use in Pregnancy

April 2023

Depression affects approximately 10% of pregnant people and is associated with adverse parental and foetal outcomes. This bulletin presents antidepressant options during pregnancy.

Treatment of Nausea and Vomiting in Pregnancy

January 2023

Nausea and vomiting are common in pregnancy, affecting up to 80% of women. This bulletin summarises the available treatment options for these patients.

Crushing nirmatrelvir+ritonavir (Paxlovid®) tablets

December 2022

Nirmatrelvir+ritonavir (Paxlovid®) is available for patients with COVID-19 who are at high risk of severe disease. This bulletin provides recommendations for administration to patients who have enteral feeding tubes or swallowing difficulties.

Pharmacokinetic medicines interactions with probenecid

November 2022

This bulletin highlights how probenecid significantly alters the clearance and exposure of many commonly used medicines through inhibition of renal organic anion transporters and glucuronidation, with several interactions deliberately exploited in clinical practice. It provides practical, clinically focused guidance on when to monitor, adjust doses, or avoid combinations to optimise efficacy and minimise toxicity.

Taking Complementary and Alternative Products with Your Medicines

November 2022

The use of complementary and alternative products (CAPs) such as herbals, dietary supplements, probiotics and homeopathic products is very common. However, most products sold in Aotearoa NZ are unregulated. This bulletin describes the problems reported regarding the quality of CAPs.

Morphine and Oxycodone – Similarities and Differences

February 2016

Note this bulletin is older than 5 years old and the content may no longer be accurate

Analgesics in Older People

February 2016

Note this bulletin is older than 5 years old and the content may no longer be accurate

Opioids and Laxatives

December 2015

Note this bulletin is older than 5 years old and the content may no longer be accurate

Codeine and Tramadol

June 2015

Note this bulletin is older than 5 years old and the content may no longer be accurate

Medication Induced Hyponatraemia

December 2014

Note this bulletin is older than 5 years old and the content may no longer be accurate

Herb Drug Interactions

May 2014

Note this bulletin is older than 5 years old and the content may no longer be accurate

Drug Interactions with Statins

January 2014

Note this bulletin is older than 5 years old and the content may no longer be accurate

Prescribing in Patients with Frailty

July 2013

Note this bulletin is older than 5 years old and the content may no longer be accurate