Christchurch Medicines Information Service

Note this bulletin is older than 5 years old and the content may no longer be accurate

Note this bulletin is older than 5 years old and the content may no longer be accurate

Note this bulletin is older than 5 years old and the content may no longer be accurate

Note this bulletin is older than 5 years old and the content may no longer be accurate

Note this bulletin is older than 5 years old and the content may no longer be accurate

Aminoglycosides (gentamicin, tobramycin and amikacin) are bactericidal antibiotics used to treat infections caused by Gram-negative organisms. Therapeutic drug monitoring is recommended to ensure adequate dosing and prevent adverse effects such as nephrotoxicity and ototoxicity. Aminoglycosides d...

This page was last updated: 12 August 2022 at 4:45pm Ritonavir increases (boosts) the concentration of nirmatrelvir by inhibiting its clearance by CYP3A enzymes. This also increases the concentration of other drugs metabolised by CYP3A. The tables below provide guidance on adjusting doses of pat...